Invitrogen™ PLD2 Monoclonal Antibody (7E4D9)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA531854

Catalog No. PIMA531854

Description

MA5-31854 has been tested in indirect ELISA.

PLD2 is a peripheral membrane protein belonging to phospholipase D family with a PH domain, two PLD phosphodiesterase domains and a PX (phox homology) domain that plays a regulatory rather than catalytic role. PLD2 catalyzes the hydrolysis of phosphatidylcholine (PC) to produce phosphatidic acid and choline. PLD2 may function in regulated secretion, signal-induced cytoskeletal regulation and/or endocytosis, transcriptional regulation, and cell cycle control. It is usually stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and activated by the ADP-ribosylation factor-1 (ARF-1). PLD2 is activated by agonist stimulation of both tyrosine kinase and G protein-coupled receptors and is also known to interact with EGFR and PIP5K1A. PLD2, localized to plasma membrane caveolae, is ubiquitously expressed in most tissues.

Specifications

• Antigen: PLD2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: O14939
• Gene Symbols: Pld2
• Immunogen: Purified recombinant fragment of human PLD2 (AA: 834-933) expressed in E. coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 7E4D9
• Conjugate: Unconjugated
• Gene: Pld2
• Gene Alias: choline phosphatase 2; hPLD2; phosphatidylcholine-hydrolyzing phospholipase D2; phospholipase D gene 2; phospholipase D2; PLD 2; PLD1C; PLD2; Pldc; rPLD2
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 5338
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid