Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

PLEKHG6 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550458

Catalog No. PA550458


Add to cart

Description

Description

The antibody detects endogenous levels of total PLEKHG6 protein.

PLEKHG6 functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.
Specifications

Specifications

PLEKHG6
Polyclonal
Unconjugated
PLEKHG6
Liquid
PLEKHG6
Fusion protein corresponding to a region derived from internal residues of human pleckstrin homology domain containing, family G (with RhoGef domain) member 6
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin), Western Blot
2.4 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
Q3KR16
MyoGEF
Rabbit
IgG
100 μL
-20°C
Primary
55200
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit