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PLEKHO1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 248831AP

Catalog No. 50-173-4596


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Description

Description

CKIP1 was identified through a yeast-two hybrid screening as a protein that would interact with only one of the two catalytic subunits of the casein kinase 2 complex. CKIP1 is a pleckstrin homology domain-containing protein localized within the nucleus and at the plasma membrane that interacts with CK2alpha but not CK2alpha ft., and is thought to play a role in targeting CK2alpha to a particular cellular location. CKIP1 has been implicated in muscle differentiation and the regulation of cell morphology and actin cytoskeleton. CKIP1 can also interact with other proteins such as ATM, an upstream kinase of p53, and recruit the nuclear ATM to the plasma membrane, suggesting CKIP1 may regulate ATM function through re-localizing ATM. CKIP1 can also form a complex with the kinase AKT, leading to a down-regulation of PI3K/AKT signaling and suppression of tumor growth in vivo.
Specifications

Specifications

PLEKHO1
0.39 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q53GL0, Q9JIY0
C Jun binding protein, CK2 interacting protein 1, CKIP 1, CKIP1, CKIP-1, HQ0024c, JBP, OC120, PLEKHO1
Rabbit
IgG
150 μL
-20°C
Primary
51177, 67220
Western Blot
Unconjugated
PLEKHO1
Liquid
PLEKHO1
PLEKHO1 Fusion Protein Ag19309
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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