Plexin-B2 Armenian Hamster anti-Mouse, Clone: eBio3E7 (3E7), eBioscience™ 

Armenian Hamster Monoclonal Antibody

Manufacturer:  Invitrogen 14566582

Catalog No. 14-566-582

Description

Description: Plexin-B2 is a member of the Semaphorin receptor family. The semaphorin family consists of membrane and secreted proteins involved in attraction and repulsion of neuronal guidance cues. Plexin-B1 is a transmembrane protein that can be cleaved coverting the single chain presursor into a heterodimeric receptor. It has been shown to bind Sema4D/CD100 and is involved in axon development in mouse embryos. Sema4D also plays a role in the immune system interacting with CD72. Plexin-B2 ft.s possible role in the immune system has not been characterized. Applications Reported: This eBio3E7 (3E7) antibody has been reported for use in flow cytometric analysis, immunoprecipitation, and immunohistochemical staining. Applications Tested: This eBio3E7 (3E7) antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 µm post-manufacturing filtered.

Plexin-B2 is a member of the Semaphorin receptor family. The semaphorin family consists of membrane and secreted proteins involved in attraction and repulsion of neuronal guidance cues. Plexin-B1 is a transmembrane protein that can be cleaved coverting the single chain presursor into a heterodimeric receptor. It has been shown to bind Sema4D/CD100 and is involved in axon development in mouse embryos. Sema4D also plays a role in the immune system interacting with CD72. Plexin-B2 ft.s possible role in the immune system has not been characterized.

Specifications

• Antigen: Plexin-B2
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.2
• Gene Accession No.: B2RXS4
• Gene Alias: MM1, PLEXB2, PLXNB2, MM1KIAA0315dJ402G11.3, Nbla00445, PLEXB2, plexin B2, plexin-B2
• Host Species: Armenian Hamster
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Monoclonal
• Target Species: Mouse

• Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation
• Clone: eBio3E7 (3E7)
• Conjugate: Unconjugated
• Gene: Plxnb2
• Format: Liquid
• Gene Symbols: PLXNB2
• Isotype: IgG
• Quantity: 100 μg
• Storage Requirements: 4° C
• Primary or Secondary: Primary
• Gene ID (Entrez): 140570

For Research Use Only.