Plexin C1 (CD232) Mouse, Alexa Fluor 647, Clone: 544232, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 566249
The 544232 monoclonal antibody specifically recognizes human and mouse Plexin C1 (PLXNC1) which is also known as, Virus-encoded semaphorin protein receptor (VESPR), or CD232. Plexin C1 is a ñ210 kDa single-pass type I membrane glycoprotein that belongs to the C subgroup of the plexin family of proteins. It is expressed on monocytes, dendritic cells, and neutrophils, as well as, some B lymphocytes and neuronal cells. Plexin C1 binds to Semaphorin 7A (CD108) and the viral semaphorin-like protein, A39R. Plexin C1 reportedly plays a role in cellular adhesion, migration, and phagocytosis.Alexa Fluor™ 647 conjugates are highly photostable and remain fluorescent over a broad pH range. The excitation and emission maxima are nearly identical to those of APC. However, APC tends to be brighter while Alexa Fluor™ 647 is more optimal for intracellular applications. This fluorochrome exhibits uncommon photostability, making it an ideal choice for use in fluorescence microscopy. Due to nearly identical excitation and emission properties but different spillover characteristics, APC and Alexa Fluor™ 647 cannot be used simultaneously.
|Plexin C1 (CD232)|
|Aqueous buffered solution containing ≤0.09% sodium azide.|
|CD232, Plexin-C1, plexinC1, PLXC1, PLXN-C1, PLXNC1, VESPR|
|Human Plexin C1 Recombinant Protein|
|The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to Alexa Fluor™ 647 under optimum conditions, and unreacted Alexa Fluor™ 647 was removed.|
|Alexa Fluor 647|
|Mouse IgG2b, κ|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
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