PLGF Antibody (PLGF/94), Alexa Fluor™ 594, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP234710AF594

Catalog No. NP234710A94

Description

PLGF Monoclonal specifically detects PLGF in Human samples. It is validated for ELISA.

Specifications

• Antigen: PLGF
• Classification: Monoclonal
• Conjugate: Alexa Fluor 594
• Formulation: 50 mM sodium borate with 0.05% sodium azide
• Gene Symbols: PGF
• Immunogen: Recombinant human PLGF protein (Uniprot: P49763)
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include Fibroblast Growth Factor (FGF), Platelet Derived Growth Factor (PDGF), Vascular Endothelial Growth Factor (VEGF) and Placenta Growth Factor (PLGF). Placenta growth factor (PLGF) is a secreted protein primarily produced by placental trophoblasts but also expressed in other endothelial cells and tumors. There are three isoforms, PLGF-1, PLGF-2, and PLGF-3. PLGF-2 is expressed up until week 8 in the placenta; the placental tissues continuously express PLGF-1 and PLGF-3 but only PLGF-1 is found in colon and mammary carcinomas. PLGF acts to stimulate angiogenesis, endothelial growth and migration. PLGF is a powerful promoter of tumor growth and is upregulated in some cancers, and PLGF is thought to aid in atherosclerotic lesions and neovascular growth surrounding the lesion. Also, P
• Content And Storage: Store at 4°C in the dark.

• Applications: Western Blot, ELISA
• Clone: PLGF/94
• Dilution: Western Blot, ELISA
• Gene Alias: D12S1900, PGFL, placenta growth factor, placental growth factor, placental growth factor, vascular endothelial growth factor-related protein, PlGF, PlGF-2, PLGFplacental growth factor-like, SHGC-10760
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Research Discipline: Angiogenesis
• Gene ID (Entrez): 5228.0
• Target Species: Human
• Isotype: IgG1 κ