Invitrogen™ PLLP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120398

Catalog No. PIPA5120398

Description

Positive test controls include: Mouse brain, Rat brain, Rat kidney. The target is usually found in the following locations: Membrane, Multi-pass membrane protein. Immunogen sequence: MAEFPSKVST RTSSPAQGAE ASVSALRPDL GFVRSRLGAL MLLQLVLGLL VWALIADTPY HLYPAYGWVM FVAVFLWLVT IVLFNLYLFQ LHMKLYMVPW.

Plasmolipin is an 18 kDa membrane-bound proteolipid that belongs to the tetraspan (4TM) family, a rapidly growing group of myelin-associated proteins. Many of these proteins could be linked to human hereditary demyelinating neuropathies. Studies indicate that plasmolipin is a component of the cytoskeletal structure and has been localized to the apical surface of tubular epithelial cells. It has been shown that, upon addition to lipid bilayers, plasmolipin induces formation of ion channels that are both voltage-dependent and potassium-specific. Plasmolipin was originally isolated from kidney tissue. Subsequently, it has been shown to be widely expressed, not only being present in kidney, but also in the nervous system, thymus, testis, lung, and thyroid gland.

Specifications

• Antigen: PLLP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PLLP
• Gene Alias: 0610010I06Rik; AV001002; Plapi; Plasma membrane proteolipid; plasma membrane proteolipid (plasmolipin); plasmolipin; PLLP; PMLP; Tm4sf11; transmembrane 4 superfamily member 11; transmembrane 4 superfamily member 11 (plasmolipin)
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64364, 67801
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.15 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P47987, Q9DCU2
• Gene Symbols: PLLP
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PLLP (NP_057077.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG