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PLX 647 dihydrochloride, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
10mg
50mg
This item is not returnable. View return policy
1779796-38-1
C21H19Cl2F3N4
455.31
MVMKWLRKACAUTB-UHFFFAOYSA-N
plx 647 dihydrochloride,5-1h-pyrrolo 2,3-b pyridin-3-ylmethyl-n-4-trifluoromethyl phenyl methyl-2-pyridinamine dihydrochloride
78243730
This item is not returnable. View return policy
1779796-38-1
C21H19Cl2F3N4
455.31
MVMKWLRKACAUTB-UHFFFAOYSA-N
plx 647 dihydrochloride,5-1h-pyrrolo 2,3-b pyridin-3-ylmethyl-n-4-trifluoromethyl phenyl methyl-2-pyridinamine dihydrochloride
78243730

Potent dual Fms/KIT inhibitor

Potent dual KIT/Fms inhibitor (IC50 values are 16 and 28 nM respectively). Inhibits BCR-FMS cell proliferation and osteoclast differentiation in vitro (IC50 values are 92 and 170 nM respectively). Attenuates LPS-induced TNFα and IL-6 release, mast cell activation and macrophage kidney proliferation in vivo.

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Quantity 10mg
Color White
Formula Weight 455.3
Physical Form Solid
Percent Purity >98%
Chemical Name or Material PLX 647 dihydrochloride

Recommended Storage : Desiccate at RT