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  6. PLX 647 dihydrochloride, Tocris Bioscience™

PLX 647 dihydrochloride, Tocris Bioscience™

Catalog Number 510210R
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
1779796-38-1
C21H19Cl2F3N4
455.31
MVMKWLRKACAUTB-UHFFFAOYSA-N
plx 647 dihydrochloride, 5-1h-pyrrolo 2,3-b pyridin-3-ylmethyl-n-4-trifluoromethyl phenyl methyl-2-pyridinamine dihydrochloride
78243730
This item is not returnable. View return policy
1779796-38-1
C21H19Cl2F3N4
455.31
MVMKWLRKACAUTB-UHFFFAOYSA-N
plx 647 dihydrochloride, 5-1h-pyrrolo 2,3-b pyridin-3-ylmethyl-n-4-trifluoromethyl phenyl methyl-2-pyridinamine dihydrochloride
78243730

Description

Potent dual Fms/KIT inhibitor

Potent dual KIT/Fms inhibitor (IC50 values are 16 and 28 nM respectively). Inhibits BCR-FMS cell proliferation and osteoclast differentiation in vitro (IC50 values are 92 and 170 nM respectively). Attenuates LPS-induced TNFα and IL-6 release, mast cell activation and macrophage kidney proliferation in vivo.
Color White
Quantity 10 mg
Formula Weight 455.3
Percent Purity >98%
Physical Form Solid
Chemical Name or Material PLX 647 dihydrochloride

Safety and Handling

Recommended Storage Desiccate at RT
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