Invitrogen™ PMP22 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA575204

Catalog No. PIPA575204

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Peripheral Myelin Protein 22 (PMP22) is a 160 amino acid glycoprotein which is a member of the claudin family and is thought to play an important role in the structure of peripheral nerve myelin. Irregularities in its gene results in hereditary demyelinating neuropathies. PMP22 protein is present in the compact myelin of adult human peripheral nerve and its distribution mimics that of Myelin Protein zero (P0).

Specifications

• Antigen: PMP22
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PMP22
• Gene Alias: 22kDa; Cd25; CMT1A; CMT1E; DSS; GAS3; GAS-3; Growth arrest-specific protein 3; HMSNIA; HNPP; peripheral myelin; peripheral myelin protein 22; peripheral myelin protein 22 kDa; PMP22; PMP-22; Protein CD25; SAG; schwann cell membrane glycoprotein; Sp110; SR13 myelin protein; Tr; trembler
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18858, 5376
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P16646, Q01453
• Gene Symbols: PMP22
• Immunogen: Synthetic peptide corresponding to amino acids 120-160 of Human GAS3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG