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PMP70 Rabbit anti-Human, Mouse, Rat, Alexa Fluor® 555, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA1650A555

Catalog No. PIPA1650AZ


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Description

Description

PA1650A555 immunizing peptide corresponds to amino acid residues 644-659 from rat PMP70. This sequence is completely conserved in mouse PMP70 and differs from human PMP70 by a single amino acid substitution. The immunizing peptide (Cat. No. PEP-038) is available for use in neutralization and control experiments.

Peroxisomes are single membrane organelles which are involved with many important biochemical pathways and are found in almost all eukaryotic cells. Various toxins including, phenols, alcohols, and aldehydes are targeted for modification by peroxisomes. Long chain fatty acid metabolism via beta-oxidation is also mediated by this organelle. Loss of peroxisomal functions may result in diseases such as Zellweger syndrome, hyperpipecolic acidemia, neonatal adrenoleukodystrophy, and infantile Refsum""e;s disease. Peroxisomal membrane protein 70 (PMP70) is an abundant, integral membrane protein of the peroxisome. This protein is induced by treatment with hypolipidemic agents in parallel with peroxisome proliferation and stimulation of the peroxisomal beta-oxidation enzymes.
Specifications

Specifications

PMP70
Polyclonal
Alexa Fluor™ 555
ABCD3
Liquid
ABCD3
Synthetic Peptide: C N(644) Y E F K K I T E D T V E F G S(659)
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunofluorescence
1 mg/mL
PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
P28288, P55096, P16970
AI313901, ABC43, PMP68, Pxmp1, ZWS2, PXMP1, PMP70, AU018866, AW146054
Rabbit
IgG
50 μL
4° C, store in dark, DO NOT FREEZE!
Primary
19299, 25270, 5825
Documents
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