Tocris Bioscience PMX 464
Putative inhibitor of the Trx-TrxR system; antiproliferative
Manufacturer: Tocris Bioscience 4996/50
DescriptionPutative inhibitor of the thioredoxin-thioredoxin reductase (Trx-TrxR) system. Shown to inhibit Trx and induce a G1/S block in HT29 cells; inhibits cell proliferation in various colorectal cancer cell lines and MCF7 cells. Also elicits an anti-inflammatory response in A549 cells.
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