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PNMA2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 164451AP

Catalog No. 50-173-0948


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Description

Description

In patients with cancer, symptoms of limbic and brain-stem dysfunction may result from a para-neoplastic disorder. Two proteins, Ma1 and Ma2, were discovered by presence of autoantibodies against them. Antibodies to Ma1 and Ma2 proteins identify a paraneoplastic disorder that affects the limbic system, brain stem, and cerebellum. These autoantibodies were used to clone Ma2, which codes for a protein (Ma2) that was recognized by serum from the 10 patients, but not by serum from 344 control subjects. Ma2 was selectively expressed by normal brain tissue and by the testicular tumors of the patients. Ma2 shares homology with Ma1, a "brain-testis-cancer" gene related to other para-neoplastic syndromes and tumors.
Specifications

Specifications

PNMA2
0.19 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q8BHK0, Q9UL42
40 kDa neuronal protein, KIAA0883, MA2, MM2, Onconeuronal antigen Ma2, paraneoplastic antigen MA2, PNMA2, RGAG2
Rabbit
IgG
150 μL
-20°C
Primary
10687, 239157, 305977
Western Blot
Unconjugated
PNMA2
Liquid
PNMA2
PNMA2 Fusion Protein Ag10289
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Documents
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