Podocalyxin Like, Mouse anti-Human, Alexa Fluor 350, Clone: PODXL/2606, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP276326AF350

Catalog No. NB009344

Description

Podocalyxin Like Monoclonal antibody specifically detects Podocalyxin Like in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry (Paraffin).

Specifications

• Antigen: Podocalyxin Like
• Clone: PODXL/2606
• Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin
• Format: Conjugated, Purified
• Gene Symbols: PODXL
• Immunogen: Recombinant fragment of human Podocalyxin (around aa 310-447) (exact sequence is proprietary)
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Storage Requirements: Store at 4°C in the dark.
• Monoclonal or Polyclonal: Monoclonal
• Target Species: Human

• Applications: Immunohistochemistry, Immunohistochemistry (Paraffin)
• Conjugate: Alexa Fluor 350
• Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
• Gene Alias: Gp200MGC138240, PCLP1, PCLP-1, PCLPGCTM-2 antigen, PCpodocalyxin, podocalyxin-like, Podocalyxin-like protein 1
• Host Species: Mouse
• Isotype: IgG2b Kappa
• Quantity: 0.1 mL
• Research Discipline: Cancer, Cell Biology, Cellular Markers, Hematopoietic Stem Cell Markers, Stem Cell Markers
• Primary or Secondary: Primary
• Test Specificity: Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.