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Podocalyxin Like Mouse anti-Human, Mouse, Rat, Rabbit, Alexa Fluor 594, Clone: 3D3, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP233108AF594
DescriptionPodocalyxin Like Monoclonal antibody specifically detects Podocalyxin Like in Human,Mouse,Rat,Rabbit samples. It is validated for Western Blot,Flow Cytometry,ELISA,Immunohistochemistry,Immunocytochemistry,Immunofluorescence,Immunohistochemistry (Paraffin),Immunohistochemistry (Frozen).
|Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen|
|Gp200MGC138240, PCLP1, PCLP-1, PCLPGCTM-2 antigen, PCpodocalyxin, podocalyxin-like, Podocalyxin-like protein 1|
|Store at 4°C in the dark.|
|Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.|
|ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot|
|Alexa Fluor™ 594|
|50 mM sodium borate with 0.05% sodium azide|
|A recombinant protein fragment containing the intracellular, transmembrane, and part of the extracellular domain of human podocalyxin was used as the immunogen to generate the 3D3, 4F10 and 2A4 podocalyxin antibody clones (Karshaw, 1997). The 3D3 antibody recognizes an epitope in the extracellular domain, and both the 4F10 and 2A4 antibody clones recognize epitopes in the intracellular domain of podocalyxin.|
|Human, Mouse, Rabbit, Rat|