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Podocalyxin Like Mouse anti-Human, Mouse, Rat, Rabbit, Alexa Fluor™ 750, Clone: 3D3, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP233108AF750

Catalog No. NP233108A70


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Description

Description

Podocalyxin Like Monoclonal antibody specifically detects Podocalyxin Like in Human, Mouse, Rat, Rabbit samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen).
Specifications

Specifications

Podocalyxin Like
3D3
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Conjugated, Purified
PODXL
A recombinant protein fragment containing the intracellular, transmembrane, and part of the extracellular domain of human podocalyxin was used as the immunogen to generate the 3D3, 4F10 and 2A4 podocalyxin antibody clones (Karshaw, 1997). The 3D3 antibody recognizes an epitope in the extracellular domain, and both the 4F10 and 2A4 antibody clones recognize epitopes in the intracellular domain of podocalyxin.
Protein G purified
Cancer, Cell Biology, Cellular Markers, Embryonic Stem Cell Markers, Hematopoietic Stem Cell Markers, Stem Cell Markers
Primary
5420.0
Human, Mouse, Rabbit, Rat
ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Alexa Fluor™ 750
50 mM sodium borate with 0.05% sodium azide
Gp200MGC138240, PCLP1, PCLP-1, PCLPGCTM-2 antigen, PCpodocalyxin, podocalyxin-like, Podocalyxin-like protein 1
Mouse
IgG1
0.1 mL
Store at 4°C in the dark.
Monoclonal
Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.
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