POLI Mouse anti-Human, Clone: OTI3B5, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526503
DescriptionMammalian Pol ι owns an unusual combination of properties: it is stimulated by Mn2+ ions, can bypass some DNA lesions and misincorporates ""G"" opposite template ""T"" more frequently than incorporates the correct ""A."" It has been proposed that POLI involves in immunoglobulin somatic hypermutation (SHM), bypass of deaminated cytosines, several adducts of the purine bases. DNA strand crosslinks and is involved in DNA repair under oxidative stress.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|DNA polymerase iota;Eta 2;Eta2;POLI;POLI_HUMAN;Polymerase (DNA directed) iota;RAD 30B;RAD30 homolog B;RAD30, S. cerevisiae, homolog of;RAD30B;RAD3OB;|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 458-740 of POLI produced in E.coli|
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