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POLI Mouse anti-Human, Clone: OTI3B5, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526503

Catalog No. PIMA526503


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Description

Description

Mammalian Pol ι owns an unusual combination of properties: it is stimulated by Mn2+ ions, can bypass some DNA lesions and misincorporates ""G"" opposite template ""T"" more frequently than incorporates the correct ""A."" It has been proposed that POLI involves in immunoglobulin somatic hypermutation (SHM), bypass of deaminated cytosines, several adducts of the purine bases. DNA strand crosslinks and is involved in DNA repair under oxidative stress.
Specifications

Specifications

POLI
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q9UNA4
DNA polymerase iota;Eta 2;Eta2;POLI;POLI_HUMAN;Polymerase (DNA directed) iota;RAD 30B;RAD30 homolog B;RAD30, S. cerevisiae, homolog of;RAD30B;RAD3OB;
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
11201
Immunohistochemistry (Paraffin), Western Blot
OTI3B5
Unconjugated
POLI
Liquid
POLI
Human recombit protein fragment corresponding to amino acids 458-740 of POLI produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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