Invitrogen™ POLR2H Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA593307

Catalog No. PIPA593307

Description

Immunogen sequence: MAGILFEDIF DVKDIDPEGK KFDRVSRLHC ESESFKMDLI LDVNIQIYPV DLGDKFRLVI ASTLYEDGTL DDGEYNPTDD RPSRADQFEY VMYGKVYRIE GDETSTEAAT RLSAYVSYGG LLMRLQGDAN NLHGFEVDSR VYLLMKKLAF; Positive Samples: SW480, MCF-7, HL-60, 293T, Mouse spleen, Mouse brain, Mouse thymus; Cellular Location: Nucleus, nucleolus.

Eukaryotes produce 3 distinct classes of RNA polymerase, Pol I, II and III. Each polymerase is responsible for the synthesis of a different class of RNA. RNA polymerase I (Pol I) transcribes the rRNA (ribosomal RNA) genes for the precursor of the 28S, 18S, and 5. 8S molecules of the ribosome. RNA polymerase II transcribes protein-encoding genes into mRNA (messenger RNA) and snRNA (small nuclear RNA) genes into snRNAs that influence the processing of other classes of RNA. RNA polymerase III (Pol III) transcribes the 5S rRNA genes and all of the tRNA (transfer RNA) genes. Each class of RNA polymerase is assembled from 9 to 15 different polypeptides. The RPB6 and RPB8 subunits are shared by all 3 RNA polymerases.

Specifications

• Antigen: POLR2H
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: POLR2H
• Gene Alias: ABC3; DNA-directed RNA polymerase II subunit H; DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide; DNA-directed RNA polymerases I, II, and III subunit RPABC3; hRPB8; hsRPB8; POLR2H; polymerase (RNA) II (DNA directed) polypeptide H; polymerase (RNA) II subunit H; RGD1561203; RNA polymerase II subunit H; RNA polymerases I, II, and III subunit ABC3; RPABC3; RPB17; RPB8; RPB8 homolog
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 245841, 498109, 5437
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunoprecipitation, Western Blot
• Concentration: 1.33 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P52434, Q923G2
• Gene Symbols: POLR2H
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human POLR2H (NP_0062232).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG