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POLR3A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 175301AP

Catalog No. 50-173-1627


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Description

Description

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. POLR3A is the largest and catalytic core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. It forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol III. A bridging helix emanates from RPC1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol III by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition.
Specifications

Specifications

POLR3A
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O14802
hRPC155, POLR3A, RNA polymerase III subunit C1, RPC1, RPC155
Rabbit
IgG
150 μL
-20°C
Primary
11128, 218832, 361102
Western Blot
Unconjugated
POLR3A
Liquid
Polr3a
POLR3A Fusion Protein Ag11536
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Documents
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