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POLR3H Mouse anti-Human, Clone: OTI5A12, lyophilized, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner CF809442

Catalog No. 50-166-9497


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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

RPC8 is DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. It is plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. It is acting as nuclear and cytosolic DNA sensor involved in innate immune response. It can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway.
Specifications

Specifications

POLR3H
Monoclonal
Unconjugated
POLR3H
Lyophilized
POLR3H
Full length human recombit protein of human POLR3H produced in E.coli.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Western Blot
OTI5A12
PBS with 8% trehalose and no preservative; pH 7.3
Q9Y535
RPC22.9, RPC8
Mouse
IgG2a
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
171568
SDS
Documents
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