POMK Mouse anti-Human, Clone: OTI2B10, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526678
DescriptionThis gene encodes a protein that may be involved in the presentation of the laminin-binding O-linked carbohydrate chain of alpha-dystroglycan (a-DG), which forms transmembrane linkages between the extracellular matrix and the exoskeleton. Some pathogens use this O-linked carbohydrate unit for host entry. Loss of function compound heterozygous mutations in this gene were found in a human patient affected by the Walker-Warburg syndrome (WWS) phenotype. Mice lacking this gene contain misplaced neurons (heterotopia) in some regions of the brain, possibly from defects in neuronal migration. Alternative splicing of this gene results in multiple transcript variants.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|POMK, MDDGA12, MDDGC12, SGK196|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 141-350 of SGK196 produced in E.coli|
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