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PON1 Mouse anti-Human, Clone: 4G8D3, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524800

Catalog No. PIMA524800


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Description

Description

The paraoxonase (PON) gene-family in humans has three members, PON1, PON2, and PON3, aligned next to each other on the long arm of chromosome 7q21.3-22.1. PON1 of these is synthesized primarily in the liver and a portion is secreted into the plasma, where it is associated with high density lipoproteins (HDL). And It hydrolyzes the active metabolites of several other organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon), as well as nerve agents such as sarin, soman and VX (lethal nerve agent). The PON1 polymorphism may be responsible for neurodegeneration and considered to be an independent risk factor for Parkinson ft.s disease.
Specifications

Specifications

PON1
Monoclonal
1 mg/mL
PBS with 0.5% proprietary stabilizer and 0.05% sodium azide; pH 7.4
P27169
A-esterase 1, Aromatic esterase 1, arylesterase B-type, EC 3.1.1.2, EC 3.1.1.81, EC 3.1.8.1, ESAesterase A, K-45, MVCD5, paraoxonase 1, PON 1, PONparaoxonase B-type, serum aryldiakylphosphatase, Serum aryldialkylphosphatase 1, serum paraoxonase/arylesterase 1
Mouse
IgG1
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
5444
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
4G8D3
Unconjugated
PON1
Liquid
PON1
Partial recombit human PON1 (between residues 1-200) expressed in E. coli.
Ammonium sulfate precipitation
RUO
Antibody
Monoclonal
Human
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