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Invitrogen™ Porcine CCL-4/MIP-1 beta ELISA Kit Non-distribution product as customer accommodation.

Porcine CCL-4/MIP-1 beta quantitates porcine CCL-4/MIP-1 beta in serum, plasma, supernatant.

$491.00 - $2205.00

Specifications

Regulatory Status Research Use Only
Storage Requirements 2°C to 8°C
Target CCL4
Product Type ELISA
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
ES3RBX5 Non-distribution product as customer accommodation.
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Invitrogen™
ES3RBX5
5 x 96 Tests
Each for $2,205.00
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ES3RB Non-distribution product as customer accommodation.
View Documents
Invitrogen™
ES3RB
96 Tests
Each for $491.00
Add to cart
 
Description

Description

Porcine CCL-4/MIP-1 beta quantitates porcine CCL-4/MIP-1 beta in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant porcine CCL-4/MIP-1 beta.

CCL4 (macrophage inflammatory protein 1-beta, MIP1B) belongs to the intercrine beta (chemokine CC) family. Functionally, CCL4 is involved in chemotactic and proinflammatory effects, and homeostasis. CCL4 is produced by macrophages upon stimulation by bacterial endotoxins. CCL4 recruits and stimulates various inflammatory cells at sites of inflammation. CCL4 is produced by lymphocytes, macrophages and dendritic cells. Both CCL4 and the related protein CCL3 participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells. While both CCL4 and CCL3 exert similar effects on monocytes, their effect on lymphocytes differ, with CCL4 selectively attracting CD4+ lymphocytes and CCL3 selectively attracting CD8+ lymphocytes. Additionally, both have been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. The processed form of CCL4 can induce down-modulation of surface expression of the chemokine receptor CCR5, thus inhibiting the CCR5-mediated entry of HIV-1 in T cells. CCL4 binds with high affinity to CCR5 receptors.
Specifications

Specifications

Research Use Only
CCL4
Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
4 hr 45 min
Serum, Plasma, Supernatant
2°C to 8°C
ELISA
0.2 ng/mL
1 hr 20 min
Plasma, 50 µL; Supernatant, 50 µL; Serum, 50 µL
SDS
Product Certifications
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