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Invitrogen™ Porcine IL-17F ELISA Kit Non-distribution product as customer accommodation.

Porcine IL-17F quantitates porcine IL-17F in serum, plasma, supernatant.

$491.00 - $2205.00

Specifications

Regulatory Status Research Use Only
Storage Requirements 2°C to 8°C
Target IL-17 F
Product Type ELISA
Kit Contents Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
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Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
ES11RBX5 Non-distribution product as customer accommodation.
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Invitrogen™
ES11RBX5
5 x 96 Tests
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ES11RB Non-distribution product as customer accommodation.
View Documents
Invitrogen™
ES11RB
96 Tests
Each for $491.00
Add to cart
 
Description

Description

Porcine IL-17F quantitates porcine IL-17F in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant porcine IL-17F.

IL-17F (Interleukin 17F, CTLA-8)) is a cytokine belonging to the IL-17 family that is produced by inflammatory cells such as activated T cells, mast cells, and basophils. IL-17F is involved in allergic airway inflammation, and can induce several cytokines, chemokines, and adhesion molecules in bronchial epithelial cells, vein endothelial cells, fibroblasts, and eosinophils. IL-17F may be secreted as a homodimer, or a heterodimer with IL17A. It acts by binding to the type I receptor, IL-17R, aiding recruitment of monocytes and neutrophils at the site of inflammation by increasing chemokine production. IL-17F also stimulates induction of other pro-inflammatory cytokines TNF alpha, IL-1 beta, IL-6, and IL-8, and reports strongly suggest the involvement of IL-17 in several chronic inflammatory diseases such as rheumatoid arthritis, psoriasis and multiple sclerosis. TGF-beta (differentiation) and IL-23 (expansion) are required for induction and maintenance of Th17 (IL-17 producing) cells, which in turn induce the other pro-inflammatory cytokines. IL-17F is produced, and exists, as a homo-dimer, with homology to a herpes virus early protein, is one of the six members (IL-17A-F) of this cytokine family, and is well characterized and highly expressed by activated effector memory T cells. IL-17F has been found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1.
Specifications

Specifications

Research Use Only
IL-17 F
Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
4 hr 45 min
Serum, Plasma, Supernatant
2°C to 8°C
ELISA
6 pg/mL
1 hr 20 min
Plasma, 50 µL; Supernatant, 50 µL; Serum, 50 µL
SDS
Product Certifications
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