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PPARA Mouse anti-Human, Clone: OTI2F3, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA503542

Catalog No. 50-167-4406


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Description

Description

Peroxisome proliferator-activated receptor alpha (PPARA) is a member of the nuclear hormone receptor subfamily. Upon activation, PPARA forms heterodimers with retinoid X receptors (RXRs), and functions to regulatetranscrption of specific gene sequences. In particular, PPARA controls genes involved in the peroxisomal and mitochondrial beta oxidation pathways, fatty acid uptake, and triglyceride catabolism in the liver and skeletal muscle. PPARA also has anti-inflammatory and anti-proliferative effects and prevents the proatherogenic effects of cholesterol accumulation in macrophages by stimulating cholesterol efflux. PPARA is the main target of fibrate drugs; hypolipidemic agents used in the treatment of dyslipidemia and the prevention of cardiovascular disease. They could also be used for the treatment of type II diabetes.
Specifications

Specifications

PPARA
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q07869
NR1C1, PPAR, PPARalpha, hPPAR
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
5465
Immunocytochemistry, Immunofluorescence, Western Blot
OTI2F3
Unconjugated
PPARA
Liquid
PPARA
Human recombit protein fragment corresponding to amino acids 145-420 of human PPARA produced in E.coli.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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