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PPP1R3B Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA5107219

Catalog No. PIPA5107219


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Description

Description

Sequence homology: Cow: 93%; Dog: 93%; Goat: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%

Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in hepatocytes.
Specifications

Specifications

PPP1R3B
Polyclonal
Unconjugated
PPP1R3B
Liquid
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
79660
Western Blot
0.5 mg/mL
PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
Q86XI6
PPP1R3B
Synthetic peptide located within the following region: LSSKNEASGM VAPAVQEKKV KKRVSFADNQ GLALTMVKVF SEFDDPLDMP
Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Documents
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