PPP1R7 Mouse anti-Canine, Human, Rat, Clone: OTI4F9, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524968
DescriptionIn eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase 1 (PP1) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit. Sds22, also known as PPP1R7 (protein phosphatase 1, regulatory (inhibitor) subunit 7), is a 360 amino acid protein that localizes to the nucleus and contains ten LRR (leucine rich) repeats. Expressed in a variety of tissues, Sds22 functions as a regulatory subunit of the PP1 complex, suggesting a role in protein regulation throughout the cell. Multiple isoforms of Sds22 exist due to alternative splicing events.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|Protein phosphatase 1 regulatory subunit 7, Protein phosphatase 1 regulatory subunit 22, SDS22|
|-20° C, Avoid Freeze/Thaw Cycles|
|100855698, 301618, 5510|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of PPP1R7 produced in HEK293T cell|
|Canine, Human, Rat|
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