PPP4R2 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA550130
The antibody detects endogenous levels of total PPP4R2 protein.Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on ft.Ser-140 ft. (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
|Synthesized peptide derived from internal of human PP4R2.|
|Antigen affinity chromatography|
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.4|
|MGC131930, PP4R2, protein phosphatase 4, regulatory subunit 2,|
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