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PPPDE1/PNAS4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 205171AP

Catalog No. 50-173-2931


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Description

Description

This antibody specifically recognized endogenous PPPDE1, which has been confirmed by siRNA test.

PNAS4 is a highly conserved protein that shares high homology from plants to animals. It was initially identified as a putative apoptosis-related protein in the human acute promyelocytic leukemia cell line NB4. PNAS4 is activated during the early response to DNA damage and can inhibit proliferation via apoptosis when overexpressed in some tumor cells such as U2OS, SKOV3, and A549. PNAS4 inhibits tumor cell proliferation through the following mechanisms: (i) overexpression of PNAS4 causes S phase arrest by regulating the expression of cell cycle-related proteins and (ii) PNAS4 induces apoptosis through the mitochondrial apoptosis pathway. Recent evidence has shown that PNAS4 may be involved in the genesis of some cancers and could be a potential candidate for lung cancer therapy alone or in combination with gemcitabine. At least two isoforms of PNAS4 are known to exist.
Specifications

Specifications

PPPDE1/PNAS4
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q5XIT6, Q9BSY9, Q9D291
DESI2, Desumoylating isopeptidase 2, FAM152A, PNAS 4, PPPDE1
Rabbit
IgG
150 μL
-20°C
Primary
289277, 51029, 78825
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
DESI2
Liquid
Desi2
PPPDE1/PNAS4 Fusion Protein Ag14352
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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