Tocris™ PPQ 102

Potent, voltage-independent CFTR chloride channel inhibitor

Manufacturer: Tocris™ 4303/50

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Catalog No. 43-035-0

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For Research Use Only


    Product Type PPQ 102
    Inhibitors PPQ 102
    Purity >98
    Molecular Weight 438.48
    Quantity 50mg

    Potent, voltage-independent CFTR chloride channel inhibitor (IC50 = 90nM). Reduces the size and number of renal cysts in an embryonic kidney culture model of polycystic kidney disease. Also increases VEGF-A production from airway epithelial cells in vitro.

    • Chemical Name: 6,7-Dihydro-7,9-dimethyl-6-(5-methyl-2-furanyl)-11-phenylpyrimido[4',5':3,4]pyrrolo[1,2-a]quinoxaline-8,10(5H,9)-dione
    • Formula: C26H22N4O3
    • CAS Number: 931706-15-9
    • Solubility: Soluble to 20mM in DMSO with gentle warming
    • Purity: >98

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