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PRDX5 Mouse anti-Human, Clone: OTI4B12, liquid, TrueMAB™
Mouse Monoclonal Antibody
Supplier: OriGene TA811481
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DescriptionPeroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20-30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide|
|Full length human recombit protein of human PRDX5 produced in HEK293T cell.|
|Immunohistochemistry (Paraffin), Western Blot|
|ACR1, AOEB166, B166, HEL-S-55, PLP, PMP20, PRDX6, PRXV, SBBI10, prx-V|
|-20° C, Avoid Freeze/Thaw Cycles|
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