Invitrogen™ PRELP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578631

Catalog No. PIPA578631

Description

Positive Control: mouse heart Predicted Reactivity: Human (100%), Rat (91%), Rhesus Monkey (99%), Bovine (91%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage.

Specifications

• Antigen: PRELP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PRELP
• Gene Alias: 55 kDa leucine-rich repeat protein of articular cartilage; 7330409J17Rik; MST161; MSTP161; PRELP; Prolargin; prolargin proteoglycan; proline and arginine rich end leucine rich repeat protein; proline arginine-rich end leucine-rich repeat; proline/arginine-rich end leucine-rich repeat protein; proline-arginine-rich end leucine-rich repeat protein; SLRR2A
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 116847, 5549
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.95 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P51888, Q9JK53
• Gene Symbols: PRELP
• Immunogen: Recombinant protein encompassing a sequence within the center region of human PRELP. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG