Protein Kinase D2 Mouse anti-Human, Clone: OTI4F1, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525231
DescriptionMembers of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms ( alpha, betaI, betaII and gamma) and novel (n) PKC isoforms ( delta, epsilon, zeta, eta and theta). Patterns of expression for each PKC isoform differs among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC delta and epsilon are independent of Ca 2+. On the other hand, nPKC delta and epsilon, as well as all of the cPKC members, possess phorbol ester-binding activities and kinase activities.
|Protein Kinase D2|
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|Polycystin 2; Autosomal domit polycystic kidney disease type II protein; Polycystwin; R48321; PKD2|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of PRKD2 produced in HEK293T cell|
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