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PRODH Mouse anti-Human, Clone: OTI1H6, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527320

Catalog No. PIMA527320


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Description

Description

PRODH (proline dehydrogenase), also known as proline oxidase 2 (POX2), is a 516 amino acid protein belonging to the proline oxidase family. Induced during p53-induced apoptosis, PRODH catalyzes the first step in proline degradation by converting proline to delta-1-pyrroline-5-carboxylate. Defects in PRODH are the cause of hyperprolinemia type 1, a disorder characterized by elevated serum proline levels. Defects in PRODH may also be involved in the psychiatric and behavioral phenotypes associated with DiGeorge syndrome. Localized to the mitochondrion matrix, PRODH is expressed at higher levels in lung, brain and skeletal muscle and expressed at lower levels in heart, liver, kidney and pancreas. PRODH exists as two isoforms produced by alternative splicing.
Specifications

Specifications

PRODH
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
O43272
HSPOX2; mitochondrial; P53 induced gene 6 protein; p53-induced gene 6 protein; PIG6; PROD_HUMAN; PRODH 1; PRODH 2; PRODH; PRODH1; PRODH2; Proline dehydrogenase; proline dehydrogenase (oxidase) 1; proline dehydrogenase (proline oxidase); Proline dehydrogenase 1; Proline oxidase 2; Proline oxidase; Proline oxidase, mitochondrial precursor; SCZD4; TP53I6; tumor protein p53 inducible protein 6;
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
5625
Immunohistochemistry (Paraffin), Western Blot
OTI1H6
Unconjugated
PRODH
Liquid
PRODH
Full length human recombit protein of PRODH produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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