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Progerin Mouse anti-Human, Clone: 13A4, Active Motif™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

$116.85 - $356.95

Specifications

Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Antigen Progerin
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-199-3008 Non-distribution product as customer accommodation.
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Active MotifSupplier Diversity Partner
39966
10 μg
Each for $116.85
Add to cart
 
50-199-3007 Non-distribution product as customer accommodation.
View Documents
Active MotifSupplier Diversity Partner
39965
100 μg
Each for $356.95
Add to cart
 
Description

Description

Progerin is a 614 amino acid protein involved in Hutchinson-Gilford progeria syndrome. Progerin is most often generated by a point mutation (C1824T) in the LMNA gene that codes for lamin-A/C. This mutation activates a cryptic splice site and gives rise to a form of lamin A with a 50-amino acid internal deletion within the C-terminal domain of the protein. Approximately 80% of Hutchinson-Gilford progeria syndrome cases carry a single copy of the most common mutation, a silent point mutation, G608G (GGC > GGT), within exon 11 of the LMNA gene.
Specifications

Specifications

Monoclonal
Primary
Progerin
Unconjugated
SDS
Product Certifications
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