Progesterone Monoclonal Antibody (1188/344), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA183403

Catalog No. PIMA183403

Description

Mouse anti progesterone monoclonal antibody, clone 1188/344 is specific for progesterone, a steroid hormone synthesized from the cholesterol derivative, pregnenolone, in the cortex of the adrenal gland.

Progesterone is the major progestational steroid, secreted primarily by the corpus luteum and the placenta. Progesterone binds to the progesterone receptor, resulting in dissociation of heat shock proteins, receptor phosphorylation, and transcription activation through direct or indirect interaction with transcription factors. Progesterone acts on the uterus, the mammary glands and the brain. It is required in embryo implantation, pregcy maintece, and the development of mammary tissue for milk production. Progesterone, converted from pregnenolone, also serves as an intermediate in the biosynthesis of gonadal steroid hormones and adrenal corticosteroids. Therapeutic progesterone is a synthetic form of the endogenous hormone progesterone. This agent exerts inhibitory effects on estrogens by decreasing the number of estrogen receptors and increasing its metabolism to inactive metabolites. [National Center for Biotechnology Information. PubChem Compound Database; CID=5994]

Specifications

• Antigen: Progesterone
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Gene Alias: OHP; 11-alpha-hydroxyprogesterone; Hydroxyprogesterone alpha; hydroxyprogesterone 11; Progesterone-11a-hemisuccinate; Agolutin; Crinone; Luteohormone; Pregn-4-ene-3,20-dione; C21H30O2
• Immunogen: Progesterone conjugated to BSA
• Quantity: 200 μg
• Primary or Secondary: Primary
• Content And Storage: 4°C or -20°C if preferred
• Form: Liquid

• Applications: ELISA
• Clone: 1188/344
• Conjugate: Unconjugated
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Target Species: Chemical
• Product Type: Antibody
• Isotype: IgG2b