Prohibitin Polyclonal Antibody, Invitrogen™

Catalog No.	Quantity
PIPA124426	50 μg

Catalog No. PIPA124426

Supplier: Thermo Scientific PA124426

Description

Rabbit Polyclonal Antibody

PA1-24426 detects Prohibitin (PHB) in Human samples. PA1-24426 has been successfully used in Western Blot procedures dilute this antibody with 5% skim milk/PBS buffer. PA1-24426 immunogen corresponds to Polyclonal antibody from rabbits immunized with a synthetic peptide region of of human PHB. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3′ untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3′ untranslated region may function as a trans-acting regulatory RNA.

Specifications

• Antigen: Prohibitin
• Applications: Immunohistochemistry, Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Gene: PHB
• Gene Accession No.: P35232
• Gene Alias: PHB
• Gene Symbols: PHB
• Host Species: Rabbit
• Immunogen: Synthetic peptide region of of human PHB.
• Purification Method: Antigen affinity chromatography
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5245
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG