Thermo Scientific™ ProSwift™ RP-4H Capillary Monolithic HPLC Columns

For fast, high-resolution LC-MS separations in protein identification, biomarker discovery, and systems biology applications, use Thermo Scientific™ ProSwift™ RP-4H Capillary Monolithic HPLC Columns.

Manufacturer: Thermo Scientific™ 164922

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Catalog No. 16-492-2

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    Column Type Reversed Phase
    For Use With LC/MS
    Type Analytical Column
    Carbon Load -
    Column Chemistry Phenyl
    USP Type N/A
    Endcapped -
    Flow Rate 500 to 3000nL/min
    Max. Pressure 4950psi
    Packing Material Monolithic polymer
    Particle Size Monolith
    Temperature 70°C
    Pore Size -
    pH 1 to 14
    Stationary Phase Phenyl
    Solvents Most common Organic Solvents
    Surface Area -
    Length (Metric) 250mm
    Material Poly(ethylvinylbenzene-co-divinylbenzene)
    Description ProSwift RP-4H, medium channel
    Column Format Analytical Column
    Diameter (Metric) 0.1mm

    For fast, high-resolution LC-MS separations in protein identification, biomarker discovery, and systems biology applications, use Thermo Scientific™ ProSwift™ Monolithic HPLC Columns. Based on a ethylvinylbenzene divinylbenzene copolymer, the monolithic structure offers a high-quality alternative to traditional microparticulate sorbents, providing important advantages to the chromatographic separation. High-sensitivity proteomics and biotech applications are easily performed using these columns.

    Each monolith is a single cylindrical polymer rod containing an uninterrupted, interconnected network of flow-through channels of a specific pore size. These large channels and the monolith's nonporous surfaces provide fast mass transfer for the high-resolution and fast protein separations. The monolith morphology results in low operating backpressure, allowing the use of higher linear velocities with minimal loss of resolution.

    Advantages of High Resolution at Exceptionally High Flow Rates

    • Highest operational flow rates available
    • High throughput and improved productivity
    • Excellent stability over a wide pH range of 1 to 14
    • Outstanding reproducibility and ruggedness
    • High loading capacity
    Fast, Sensitive Protein Separations
    • High speed protein separations
    • High sensitivity for LC-MS
    • High column-to-column reproducibility
    • Wide range of column I.D. and lengths available
    • Superior lifetime
    Easy Column Installation
    • Use Thermo Scientific™ Dionex™ nanoViper™ Fingertight Fittings
    Preconcentrate and Desalt Samples   
    • Precolumns are available to preconcentrate and desalt samples.
    • You can also use Thermo Scientific™ PepSwift™ Trap Columns for preconcentration and desalting of samples consisting of peptides and proteins without negatively impacting the chromatographic performance or recovery of the compounds.
    • Change the selectivity of the separation or improve the trapping efficiency by employing various ion-pairing agents in the loading solvent and/or mobile phases.

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