Protocadherin Gamma Mouse anti-Human, Mouse, Clone: S159-5, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527615
DescriptionThe protocadherin gamma gene cluster is one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.4|
|Q9Y5F8, Q9Y5G6, Q9Y5G9, Q9Y5H1, Q9Y5H2, Q9Y5H3, O60330, Q9UN71, Q9Y5F6, Q9Y5G3, Q9Y5G7, Q9Y5F9, Q9Y5H0, Q9Y5G0, Q9Y5G1, Q9Y5G2, Q9Y5G5, Q9Y5H4, Q9UN70, Q9Y5F7, Q91XY4, Q9Y5G4, Q9Y5G8|
|PCDH gamma A, PCDH-gamma-A, PCDHGA, Protocadherin gamma A, Protocadherin gamma subfamily A, Gamma Protocadherin A (pan), Pan-Gamma-Protocadherin-A, Pan Gamma Protocadherin A|
|56099, 93700, 93711, 5098, 56097, 56111, 56113, 93703, 93704, 93706, 93708, 56101, 56105, 56108, 56114, 8641, 93702, 93709, 93716, 93717, 93723, 93724, 26025, 56098, 56100, 56106, 56110, 93699, 93701, 56102, 56103, 56104, 56112, 93707, 93710, 93712, 9708, 56107, 56109, 93713, 93714, 93715, 93722|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot|
|PCDHGA1, Pcdhga10, Pcdhga11, Pcdhga12, Pcdhga2, Pcdhga3, Pcdhga4, Pcdhga5, Pcdhga6, Pcdhga7, Pcdhga8, Pcdhga9, Pcdhgb1, Pcdhgb2, PCDHGB3, Pcdhgb4, Pcdhgb5, Pcdhgb6, Pcdhgb7, Pcdhgc3, Pcdhgc4, Pcdhgc5|
|Fusion protein corresponding to amino acids 808-931 (C-terminal cytoplasmic constant domain) of mouse Protocadherin-gamma-A1 that is shared by all 22 Gamma-protocadherins (A subfamily amino acids ∽807-930, B subfamily amino acids ∽789-912 and C subfamily amino acids ∽818-941). 99% identity with human (123/124 amino acids).|
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