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Protocadherin Gamma Mouse anti-Human, Mouse, Clone: S159-5, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527615

Catalog No. PIMA527615


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Description

Description

The protocadherin gamma gene cluster is one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
Specifications

Specifications

Protocadherin Gamma
Monoclonal
1 mg/ml
PBS with 50% glycerol and 0.1% sodium azide; pH 7.4
Q9Y5F8, Q9Y5G6, Q9Y5G9, Q9Y5H1, Q9Y5H2, Q9Y5H3, O60330, Q9UN71, Q9Y5F6, Q9Y5G3, Q9Y5G7, Q9Y5F9, Q9Y5H0, Q9Y5G0, Q9Y5G1, Q9Y5G2, Q9Y5G5, Q9Y5H4, Q9UN70, Q9Y5F7, Q91XY4, Q9Y5G4, Q9Y5G8
PCDH gamma A, PCDH-gamma-A, PCDHGA, Protocadherin gamma A, Protocadherin gamma subfamily A, Gamma Protocadherin A (pan), Pan-Gamma-Protocadherin-A, Pan Gamma Protocadherin A
Mouse
IgG1
100 μg
-20°C
Primary
56099, 93700, 93711, 5098, 56097, 56111, 56113, 93703, 93704, 93706, 93708, 56101, 56105, 56108, 56114, 8641, 93702, 93709, 93716, 93717, 93723, 93724, 26025, 56098, 56100, 56106, 56110, 93699, 93701, 56102, 56103, 56104, 56112, 93707, 93710, 93712, 9708, 56107, 56109, 93713, 93714, 93715, 93722
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
S159-5
Unconjugated
PCDHGA1
Liquid
PCDHGA1, Pcdhga10, Pcdhga11, Pcdhga12, Pcdhga2, Pcdhga3, Pcdhga4, Pcdhga5, Pcdhga6, Pcdhga7, Pcdhga8, Pcdhga9, Pcdhgb1, Pcdhgb2, PCDHGB3, Pcdhgb4, Pcdhgb5, Pcdhgb6, Pcdhgb7, Pcdhgc3, Pcdhgc4, Pcdhgc5
Fusion protein corresponding to amino acids 808-931 (C-terminal cytoplasmic constant domain) of mouse Protocadherin-gamma-A1 that is shared by all 22 Gamma-protocadherins (A subfamily amino acids ∽807-930, B subfamily amino acids ∽789-912 and C subfamily amino acids ∽818-941). 99% identity with human (123/124 amino acids).
Protein G
RUO
Antibody
Monoclonal
Human, Mouse
Documents
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