PRSS2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 150051AP
DescriptionThis gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|P00763, P07146, P07478|
|Anionic trypsinogen, PRSS2, Serine protease 2, TRY2, TRY8, TRYP2, Trypsin 2, Trypsin II|
|22072, 25052, 5645|
|Immunohistochemistry (Paraffin), Western Blot|
|PRSS2 Fusion Protein Ag6461|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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