PRUNE2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 114581AP150UL

Catalog No. 50-172-7176

Description

The calculated molecular weight of this protein is 340 kDa. Our antibody specifically recognizes the 140-150 kDa band which is an isoform or cleaved fragment of PRUNE2.

PRUNE2 gene, also named BMCC1, encodes protein prune homolog 2. PRUNE2 gene are overlapping with PCA3, one of the most prostate cancer specific markers. PRUNE2 may play an important role in regulating differentiation, survival and aggressiveness of the tumor cells. Besides its high level of expression seen in the nervous system (brain, cerebellum and spinal cord), it is also expressed at high levels in noneuroblastoma, rhabdomyosarcoma, melanoma and some osteosarcoma cell lines, whereas at only low levels in cancer cell lines of liver, breast, thyroid and colon. The Calculated molecular weight of this protein is 340 kDa.

Specifications

• Antigen: PRUNE2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PRUNE2
• Gene Alias: A214N16.3, BMCC1, BNIPXL, C9orf65, KIAA0367, Protein prune homolog 2, prune homolog 2 (Drosophila), PRUNE2, RP11 58J3.2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 158471, 293823, 353211
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.26 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: Q52KR3, Q5BJR4, Q8WUY3
• Gene Symbols: Prune2
• Immunogen: PRUNE2 Fusion Protein Ag2025
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG