PRUNE2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-7176	Proteintech Group Inc 114581AP150UL	150 μL

Description

The calculated molecular weight of this protein is 340 kDa. Our antibody specifically recognizes the 140-150 kDa band which is an isoform or cleaved fragment of PRUNE2.

PRUNE2 gene, also named BMCC1, encodes protein prune homolog 2. PRUNE2 gene are overlapping with PCA3, one of the most prostate cancer specific markers. PRUNE2 may play an important role in regulating differentiation, survival and aggressiveness of the tumor cells. Besides its high level of expression seen in the nervous system (brain, cerebellum and spinal cord), it is also expressed at high levels in noneuroblastoma, rhabdomyosarcoma, melanoma and some osteosarcoma cell lines, whereas at only low levels in cancer cell lines of liver, breast, thyroid and colon. The Calculated molecular weight of this protein is 340 kDa.

Specifications

• Antigen: PRUNE2
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: Q52KR3, Q5BJR4, Q8WUY3
• Gene ID (Entrez): 158471, 293823, 353211
• Immunogen: PRUNE2 Fusion Protein Ag2025
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: PRUNE2

• Concentration: 0.26 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: A214N16.3, BMCC1, BNIPXL, C9orf65, KIAA0367, Protein prune homolog 2, prune homolog 2 (Drosophila), PRUNE2, RP11 58J3.2
• Gene Symbols: Prune2
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody