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Thermo Scientific™ Lab Vision™ pS2/pNR-2 Estrogen-Regulated Protein Ab-2, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ pS2/pNR-2 Estrogen-Regulated Protein Ab-2, Mouse Monoclonal Antibody.

Specifications

Antigen pS2/pNR-2 Estrogen-Regulated Protein Ab-2
Clone GE2; previously R47/94
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Conjugate Unconjugated
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Products 1
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
MS199R1
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Thermo Scientific™
MS199R1
Ready-to-use for IHC (UVLP) 1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Provide accurate, reproducible results with the Thermo Scientific™ pS2/pNR-2 Estrogen-Regulated Protein Ab-2, Mouse Monoclonal Antibody.

pS2 is a cysteine-rich, 6.5kDa protein found in both estrogen-dependent (breast tumors) and estrogen-independent tissues (normal stomach mucosa). About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is primarily expressed in estrogen receptor-positive breast tumors.

Host Species: Mouse

Clone: GE2; same as R47/94

Isotype: IgG1

Species Reactivity: Human. Others not known.

Epitope: aa 57-84

Immunogen: A synthetic peptide of 28 amino acid residues corresponding to CFDDTVRGVPWCF-YPNTIDVPPEEECEF (aa 57-84) from C-terminus of human pS2 protein

Molecular Weight: 6.5kDa

Positive Control: Normal stomach or breast CA

Cellular Localization: Cytoplasmic Antibody to pS2 is reportedly useful in identifying a subset of estrogen-dependent breast tumors which may respond to endocrine therapy.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Affinity Purification

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

pS2/pNR-2 Estrogen-Regulated Protein Ab-2
Immunohistochemistry (Paraffin)
Unconjugated
RUO
Primary
IgG1
GE2; previously R47/94
Monoclonal
Murine
Cancer and Tumor Biology
A Synthetic peptide of 28 amino acid residues corresponding to CFDDTVRGVPWCF-YPNTIDVPPEEECEF (aa 57-84) from C-terminus of human pS2 protein
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