Invitrogen™ PSG3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA599870

Catalog No. PIPA599870

Description

Antibody detects endogenous levels of total PSG3.

The pregnancy-specific glycoproteins (PSGs) are a group of closely related secreted glycoproteins that are highly expressed in fetal placental syncytiotrophoblast cells. Members of the PSG protein family share a characteristic N-terminal domain that is homologous to the immunoglobulin variable region. PSGs become detectable in serum during the first two to three weeks of pregnancy and increase as the pregnancy progresses, eventually representing the most abundant fetal protein in the maternal blood at term. PSGs function to stimulate secretion of TH2-type cytokines from monocytes, and they may also modulate the maternal immune system during pregnancy, thereby protecting the semi-allotypic fetus from rejection. Eleven human PSG proteins (PSG1-PSG11) have been described.

Specifications

• Antigen: PSG3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PSG3
• Gene Alias: Carcinoembryonic antigen SG5; pregnancy specific beta-1-glycoprotein 3; pregnancy-specific beta-1-glycoprotein 3; pregnancy-specific glycoprotein 3; PS-beta-G-3; PSBG-3; PSG3; sg5
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5671
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q16557
• Gene Symbols: PSG3
• Immunogen: A synthesized peptide derived from human PSG3(Accession Q16557), corresponding to amino acid residues C394-L428.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG