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PSMB7 Mouse anti-Human, Mouse, Clone: OTI1E1, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA504368

Catalog No. 50-167-5081


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Description

Description

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon and proteolytic processing is required to generate a mature subunit. This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i (proteasome beta 10 subunit).
Specifications

Specifications

PSMB7
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P70195, Q99436
Z
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
19177, 5695
Immunohistochemistry (Paraffin), Western Blot
OTI1E1
Unconjugated
PSMB7
Liquid
Psmb7
Human recombit protein fragment corresponding to amino acids 58-277 of human PSMB7 produced in E.coli.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human, Mouse
Documents
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