PSMB7 Mouse anti-Human, Mouse, Non-human primate, Clone: OTI1D1, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525911
DescriptionThe proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon and proteolytic processing is required to generate a mature subunit. This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i (proteasome beta 10 subunit).
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|PSMB7; proteasome (prosome, macropain) subunit, beta type, 7; Z; macropain chain Z; multicatalytic endopeptidase complex chain Z; proteasome beta 7 subunit; proteasome catalytic subunit 2; proteasome subunit Z; proteasome subunit alpha; proteasome subunit beta 7|
|-20° C, Avoid Freeze/Thaw Cycles|
|19177, 5695, 694567|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 58-277 of PSMB7 produced in E.coli|
|Human, Mouse, Non-human primate|
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