Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

PSMB9 Mouse anti-Human, Clone: OTI1C4, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA525887

Catalog No. PIMA525887


Add to cart

Description

Description

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding different isoforms have been identified; both isoforms are processed to yield the same mature subunit.
Specifications

Specifications

PSMB9
Monoclonal
0.65 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
P28065
PSMB9; proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2); LMP2; MGC70470; PSMB6i; RING12; beta1i; low molecular mass protein 2; macropain chain 7; multicatalytic endopeptidase complex chain 7; proteasome beta 9 subunit; proteasome catalytic subunit 1i; proteasome chain 7; proteasome subunit beta 6i; proteasome-related gene 2
Mouse
IgG2b
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
5698
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
OTI1C4
Unconjugated
PSMB9
Liquid
PSMB9
Human recombit protein fragment corresponding to amino acids 21-219 of PSMB9 produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit