PSMB9 Mouse anti-Human, Mouse, Rat, Clone: OTI1F10, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525902
DescriptionThe proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding different isoforms have been identified; both isoforms are processed to yield the same mature subunit.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|P28076, P28077, P28065|
|PSMB9; proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2); LMP2; MGC70470; PSMB6i; RING12; beta1i; low molecular mass protein 2; macropain chain 7; multicatalytic endopeptidase complex chain 7; proteasome beta 9 subunit; proteasome catalytic subunit 1i; proteasome chain 7; proteasome subunit beta 6i; proteasome-related gene 2|
|-20° C, Avoid Freeze/Thaw Cycles|
|16912, 24967, 5698|
|Flow Cytometry, Western Blot|
|Human recombit protein fragment corresponding to amino acids 21-219 of PSMB9 produced in E.coli|
|Human, Mouse, Rat|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok