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PSMD10 Mouse anti-Human, Clone: OTI3F6, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA500781

Catalog No. 50-167-1923


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Description

Description

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.
Specifications

Specifications

PSMD10
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
O75832
dJ889N15.2, p28, p28(GANK)
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
5716
Flow Cytometry, Western Blot
OTI3F6
Unconjugated
PSMD10
Liquid
PSMD10
Full length human recombit protein of human PSMD10 produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
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