PSMD10 Mouse anti-Human, Clone: OTI3F6, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525016
DescriptionThe 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|26S proteasome non-ATPase regulatory subunit 10;26S proteasome regulatory subunit p28;Ankyrin repeat protein;dJ889N15.2;Gankyrin;Hepatocellular carcinoma-associated protein p28 II;p28;p28(GANK);Proteasome (prosome, macropain) 26S subunit, non ATPase, 10;PSD10_HUMAN;PSMD10;|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Western Blot|
|Full length human recombit protein of PSMD10 produced in HEK293T cell|
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